Emerging Infectious Diseases (Dec 2007)

Invasive Group A Streptococcal Infection in Older Adults in Long-term Care Facilities and the Community, United States, 1998–2003

  • Michael C. Thigpen,
  • Chesley L. Richards,
  • Ruth Lynfield,
  • Nancy L. Barrett,
  • Lee H. Harrison,
  • Kathryn E. Arnold,
  • Arthur L. Reingold,
  • Nancy M. Bennett,
  • Allen S. Craig,
  • Ken Gershman,
  • Paul R. Cieslak,
  • Paige Lewis,
  • Carolyn M. Greene,
  • Bernard Beall,
  • Chris A. Van Beneden

DOI
https://doi.org/10.3201/eid1312.070303
Journal volume & issue
Vol. 13, no. 12
pp. 1852 – 1859

Abstract

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Limited information exists on the incidence and characteristics of invasive group A streptococcal (GAS) infections among residents of long-term care facilities (LTCFs). We reviewed cases of invasive GAS infections occurring among persons >65 years of age identified through active, population-based surveillance from 1998 through 2003. We identified 1,762 invasive GAS cases among persons >65 years, including 1,662 with known residence type (LTCF or community). Incidence of invasive GAS infection among LTCF residents compared to community-based elderly was 41.0 versus 6.9 cases per 100,000 population. LTCF case-patients were 1.5 times as likely to die from the infection as community-based case-patients (33% vs. 21%, p<0.01) but were less often hospitalized (90% vs. 95%, p<0.01). In multivariate logistic regression modeling, LTCF residence remained an independent predictor of death. Additional prevention strategies against GAS infection in this high-risk population are urgently needed.

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