IDIOPATHIC GRANULOMATOUS MASTITIS MIMICING BREAST CANCER - A CASE REPORT

Abstract

Idiopathic granulomatous mastitis (IGM) is a rare benign disease of the breast with an unknown etiology, which mimicks the carcinoma of the breast. Its shows an increased incidence among women of the breeding ages usually developing in a single breast as an isolated lesion, clinically revealing dermal fi ndings similar to the infl ammatory carcinoma of the breast. Radiologically, the diff erential diagnosis between IGM and cancer remains to be a challenge for the physicians. Histopathologic examinations reveal intense infl ammation accompanied by non-caseifi ed granulomas constituting the characteristic features of this disease. The presence of other etiologies associated with histopathologic fi ndings of granulomatous reactions must be excluded to achieve the diagnosis of IGM. A thirty fi ve years old female patient admitted to our clinic with complaints of an erythematous tender mass, which she had realized to be present in her right breast for the last fi fteen days. Despite the two-week-convenient medical therapy, the clinical fi ndings revealed no improvement. Since the diagnostic procedures could not exclude malignancy, surgery was performed. Following resection, the specimen was evaluated histopathologically revealing the diagnosis of granulomatous mastitis. No evidences of recurrence were met in the postoperative sixth month. This case is presented to emphasize that the possibility of IGM should be kept in mind as an entity for diff erential diagnosis during the clinical evalutions of women of the breeding ages admitting with complaints of isolated breast masses that bring up the suspicion of breast cancer either clinically, or radiologically.

Keywords

• breast
• mastitis
• cancer
• granulomatous mastitis