Malaria Journal (Feb 2011)

Reductions in malaria and anaemia case and death burden at hospitals following scale-up of malaria control in Zanzibar, 1999-2008

  • Hosseini Mehran,
  • Korenromp Eline,
  • Komatsu Ryuichi,
  • Njau Ritha JA,
  • Warsame Marian,
  • Katikiti Samson,
  • Molteni Fabrizio,
  • Al-mafazy Abdul-wahiyd,
  • Ali Abdullah S,
  • Aregawi Maru W,
  • Low-Beer Daniel,
  • Bjorkman Anders,
  • D'Alessandro Umberto,
  • Coosemans Marc,
  • Otten Mac

DOI
https://doi.org/10.1186/1475-2875-10-46
Journal volume & issue
Vol. 10, no. 1
p. 46

Abstract

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Abstract Background In Zanzibar, the Ministry of Health and partners accelerated malaria control from September 2003 onwards. The impact of the scale-up of insecticide-treated nets (ITN), indoor-residual spraying (IRS) and artemisinin-combination therapy (ACT) combined on malaria burden was assessed at six out of seven in-patient health facilities. Methods Numbers of outpatient and inpatient cases and deaths were compared between 2008 and the pre-intervention period 1999-2003. Reductions were estimated by segmented log-linear regression, adjusting the effect size for time trends during the pre-intervention period. Results In 2008, for all age groups combined, malaria deaths had fallen by an estimated 90% (95% confidence interval 55-98%)(p Conclusions Scaling-up effective malaria interventions reduced malaria-related burden at health facilities by over 75% within 5 years. In high-malaria settings, intensified malaria control can substantially contribute to reaching the Millennium Development Goal 4 target of reducing under-five mortality by two-thirds between 1990 and 2015.