International Journal of Genomics (Jan 2025)

Investigation of the Significance of Blood Signatures on Sepsis-Induced Acute Lung Injury in Sepsis Within 24 Hours

  • Zaojun Fang,
  • Yuanyuan Wang,
  • Lingqi Xu,
  • Ying Lin,
  • Biao Zhang,
  • Jiaping Chen

DOI
https://doi.org/10.1155/ijog/5684300
Journal volume & issue
Vol. 2025

Abstract

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Conclusion: This study employed machine learning techniques to identify sepsis-associated genes and confirmed the importance of SLPI as a biomarker within 24 h of sepsis onset. SLPI also played a significant role in sepsis-induced ALI, suggesting its potential as a novel target for personalized medical interventions, targeted prevention, and patient screening.