Experimental study of amniotic lacrimal stent in the treatment of dry eye in castrated male rabbits

Biao Li; Qing Yuan; Pei-Wen Zhu; Qi Lin; You-Lan Min; Wen-Qing Shi; Lei Ye; Yi Shao

doi:10.3980/j.issn.1672-5123.2019.11.04

Guoji Yanke Zazhi (Nov 2019)

Experimental study of amniotic lacrimal stent in the treatment of dry eye in castrated male rabbits

Biao Li,
Qing Yuan,
Pei-Wen Zhu,
Qi Lin,
You-Lan Min,
Wen-Qing Shi,
Lei Ye,
Yi Shao

Affiliations

Biao Li: Department of Ophthalmology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Qing Yuan: Department of Ophthalmology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Pei-Wen Zhu: Department of Ophthalmology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Qi Lin: Department of Ophthalmology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
You-Lan Min: Department of Ophthalmology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Wen-Qing Shi: Department of Ophthalmology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Lei Ye: Department of Ophthalmology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Yi Shao: Department of Ophthalmology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China

DOI: https://doi.org/10.3980/j.issn.1672-5123.2019.11.04
Journal volume & issue: Vol. 19, no. 11
pp. 1834 – 1839

Abstract

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AIM:To explore the effect of amniotic lacrimal stent graft on castrated male rabbits of dry eye. METHODS: Thirty-six adult male rabbits were divided into two groups. Group A was treated with false castration, group B was pseudo-implantation group, and group C was implanted with lacrimal canal. Fluorescein(FL)staining and scoring and SⅠt examination, and confocal microscopy were performed at 2, 4, 6wk after implantation.RESULTS: The cornea of group A was smooth and clear, and the FL staining was not obvious. In group B, the cornea was rough, and the corneal epithelium was spotted with stained spots. The corneal surface of group C was smoother and more transparent than that of sham operation group and the punctate staining was not obviously. The FL staining scores and SⅠt examination were significant(PCONCLUSION: The amniotic lacrimal duct stent can significantly improve the symptoms and signs of castrated castrated male rabbit dry eye syndrome, and has a therapeutic effect.

Published in Guoji Yanke Zazhi

ISSN: 1672-5123 (Print)
Publisher: Press of International Journal of Ophthalmology (IJO PRESS)
Country of publisher: China
LCC subjects: Medicine: Ophthalmology
Website: http://ies.ijo.cn/

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