Nature Communications (Mar 2023)

Muscle cell-type diversification is driven by bHLH transcription factor expansion and extensive effector gene duplications

  • Alison G. Cole,
  • Stefan M. Jahnel,
  • Sabrina Kaul,
  • Julia Steger,
  • Julia Hagauer,
  • Andreas Denner,
  • Patricio Ferrer Murguia,
  • Elisabeth Taudes,
  • Bob Zimmermann,
  • Robert Reischl,
  • Patrick R. H. Steinmetz,
  • Ulrich Technau

DOI
https://doi.org/10.1038/s41467-023-37220-6
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 11

Abstract

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Different muscle cell types account for specific abilities in animals, yet how their diversification arose remains unclear. Here, the authors show that gene duplications of bHLH transcription factors and effector genes contributed to the diversification of muscle cell types in the sea anemone Nematostella.