Scientific Reports (Feb 2024)

Long-term complications and outcomes of augmentation cystoplasty in children with neurogenic bladder

  • Jei-Wen Chang,
  • Fang-Cheng Kuo,
  • Tzu-Ching Lin,
  • Tai-Wai Chin,
  • Ling-Yu Yang,
  • Hsin-Hung Chen,
  • Yu-Hua Fan,
  • Hui-Hsin Yang,
  • Chin-Su Liu,
  • Hsin-Lin Tsai

DOI
https://doi.org/10.1038/s41598-024-54431-z
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 10

Abstract

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Abstract Augmentation cystoplasty (AC) is an effective surgical procedure for patients with neurogenic bladder whenever conservative treatments have failed. The present study aimed to determine the risks of metabolic complications, malignancy, long-term outcomes and histopathologic changes of native bladder and the augmented intestine after AC in children with neurogenic bladder. Pediatric patients 10 years, no cases of malignancy or metaplastic changes were identified in the native bladder or augmented bowel epithelium. AC is a safe and effective procedure with low surgical and metabolic complication rates. In addition, AC provides a satisfactory continence rate and long-term protection of renal function, increases functional capacity, and regresses reflux and hydronephrosis. Individualized surveillance is recommended for the early identification of urolithiasis and metabolic disturbances.

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