International Journal of Women's Health (Jan 2023)

Clear Cell Adenocarcinoma Arising from Endometriosis in Abdominal Wall Cesarean Section Scar: A Case Report and Literature Review

  • Liu D,
  • Wei H,
  • Huang J,
  • Shen H,
  • Wang X,
  • Hu C

Journal volume & issue
Vol. Volume 15
pp. 25 – 32

Abstract

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Dong Liu,1,* Huanhuan Wei,2,* Jinyu Huang,1 Hailin Shen,3 Ximing Wang,1 Chunhong Hu1 1Radiological Department, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China; 2Academy of Medical Sciences, the People’s Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China; 3Department of Radiology, Suzhou Kowloon Hospital, Shanghai Jiaotong University School of Medicine, Suzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chunhong Hu, Email [email protected]: Endometriosis developing in a cesarean section (CS) scar is an unusual event. Malignant transformation arising on the background of scar endometriosis in the abdominal wall is extremely rare. Herein we report a case of clear cell carcinoma (CCC) arising in the abdominal wall from endometriosis tissues following CS and review previous literature.Case Presentation: A 48-year-old gravida 2 para 1 female presented with an abdominal wall mass at her CS scar, which increased in size and became painful in the last 2 years. Physical examination showed a multilocular solid mass of about 13 cm, at the previous CS scar. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a 12.8cm × 7.7cm multi-septate cystic lesion on the anterior abdominal wall, and histological examination showed that CCC was caused by the transformation of abdominal wall endometriosis (AWE).Conclusion: An endometriosis-associated malignancy should be considered in the differential with any enlarging mass in the abdominal wall scar.Keywords: cesarean section, abdominal wall endometriosis, case report

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