Vascular Health and Risk Management (Apr 2023)

A Heart-Healthy Diet for Cardiovascular Disease Prevention: Where Are We Now?

  • Diab A,
  • Dastmalchi LN,
  • Gulati M,
  • Michos ED

Journal volume & issue
Vol. Volume 19
pp. 237 – 253

Abstract

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Alaa Diab,1,2 L Nedda Dastmalchi,3 Martha Gulati,4 Erin D Michos1,5 1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; 2Department of Medicine, Greater Baltimore Medical Center, Baltimore, MD, USA; 3Division of Cardiology, Temple University Hospital, Philadelphia, PA, USA; 4Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, LA, USA; 5Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USACorrespondence: Erin D Michos, Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Blalock 524-B, 600 N. Wolfe Street, Baltimore, MD, 21287, USA, Tel +410-502-6813, Email [email protected] of Review: The relationship between cardiovascular health and diet is evolving. Lifestyle modifications including diet changes are the primary approach in managing cardiometabolic risk factors. Thus, understanding different diets and their impact on cardiovascular health is important in guiding primary and secondary prevention of cardiovascular disease (CVD). Yet, there are many barriers and limitations to adopting a heart healthy diet.Recent Findings: Diets rich in fruits, vegetables, legumes, whole grains, and lean protein sources, with minimization/avoidance of processed foods, trans-fats, and sugar sweetened beverages, are recommended by prevention guidelines. The Mediterranean, DASH, and plant-based diets have all proven cardioprotective in varying degrees and are endorsed by professional healthcare societies, while other emerging diets such as the ketogenic diet and intermittent fasting require more long-term study. The effects of diet on the gut microbiome and on cardiovascular health have opened a new path for precision medicine to improve cardiometabolic risk factors. The effects of certain dietary metabolites, such as trimethylamine N-oxide, on cardiometabolic risk factors, along with the changes in the gut microbiome diversity and gene pathways in relation to CVD management, are being explored.Summary: In this review, we provide a comprehensive up-to-date overview on established and emerging diets in cardiovascular health. We discuss the effectiveness of various diets and most importantly the approaches to nutritional counseling where traditional and non-traditional approaches are being practiced, helping patients adopt heart healthy diets. We address the limitations to adopting a heart healthy diet regarding food insecurity, poor access, and socioeconomic burden. Lastly, we discuss the need for a multidisciplinary team-based approach, including the role of a nutrition specialist, in implementing culturally-tailored dietary recommendations. Understanding the limitations and finding ways to overcome the barriers in implementing heart-healthy diets will take us miles in the path to CVD prevention and management.Keywords: cardiovascular disease, diet, guidelines, nutrition, disparities, gut microbiome

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