Nature Communications (Sep 2020)

A moonlighting role for enzymes of glycolysis in the co-localization of mitochondria and chloroplasts

  • Youjun Zhang,
  • Arun Sampathkumar,
  • Sandra Mae-Lin Kerber,
  • Corné Swart,
  • Carsten Hille,
  • Kumar Seerangan,
  • Alexander Graf,
  • Lee Sweetlove,
  • Alisdair R. Fernie

DOI
https://doi.org/10.1038/s41467-020-18234-w
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 15

Abstract

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Protein-protein interactions are thought to channel substrates between consecutive enzymes during glycolysis. Here the authors show that Arabidopsis phosphoglycerate mutase and enolase can form a substrate-channelling metabolon and also play a moonlighting role in promoting colocalization of chloroplasts and mitochondria.