Perspective for the use of adamantane-type drugs for the treatment of cerebrovascular and cardiovascular diseases

Abstract

Adamantane-type drugs are widely used in pharmacology as antimicrobial, antitumor, immunosuppressive, hormonal, hypoglycemic, analgesic, anti-inflammatory and neurotropic drugs. The review summarizes information on preclinical and clinical studies related to the treatment of various vascular pathologies. Assess the prospects for using memantine, amantadine, a number of innovative drugs for the prevention and treatment of stroke and cardiovascular diseases.

Keywords

• adamantane
• amantadine
• memantine
• vildagliptin
• 5-hydroxyadamantan-2-one
• stroke
• ischemia
• cerebrovascular disease