Combining VEGF receptor inhibitors and angiotensin-(1–7) to target renal cell carcinoma

Abstract

Resistance to tyrosine kinase inhibitors of the vascular endothelial growth factor receptor inevitably develops in most patients with metastatic kidney cancer. Our recent findings demonstrate that addition of angiotensin-(1-7) peptide can be a potential therapy that delays such resistance.

Keywords

• ace2
• rcc
• ang-(1–7)
• vegfr-tki
• resistance