187 Multi-omic single-cell profiling demonstrates that competition for fatty acids and fatty acid oxidation enables tumor-infiltrating lymphocyte function and survival

• Navin Varadarajan,
• Patrick Hwu,
• Cara Haymaker,
• Chantale Bernatchez,
• Caitlin Creasy,
• Scott Woodman,
• Jay R Adolacion,
• Michal Harel,
• Xingyue An,
• Melisa Angela Paniagua,
• Mohsen Fathi,
• Ali Rezvan,
• Tamar Geiger,
• Jonathan Robinson,
• Amit Amritkar

Affiliations

Navin Varadarajan

Department of Chemical and Biomolecular Engineering, University of Houston, Houston, Texas, USA

Patrick Hwu

Department of Melanoma, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Cara Haymaker

1The University of Texas MD Anderson Cancer Center, Bellaire, TX, USA

Chantale Bernatchez

Department of Melanoma, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Caitlin Creasy

Aff1 grid.267308.80000000092062401M.D. Anderson Cancer Centre (MDACC)University of Texas Houston TX USA

Scott Woodman

Aff21 grid.240145.60000000122914776University of Texas MD Anderson Cancer Center Houston TX USA

Jay R Adolacion

Aff3 grid.266436.30000000415699707University of Houston, University of the Philippines Houston TX USA

Michal Harel

OncoHost LTD, Binyamina, Israel

Xingyue An

Department of Chemical and Biomolecular Engineering, University of Houston, Houston, Texas, USA

Melisa Angela Paniagua

1University of Houston, Houston, TX, USA

Mohsen Fathi

1University of Houston, Houston, TX, USA

Ali Rezvan

1University of Houston, Houston, TX, USA

Tamar Geiger

3Tel Aviv University, Israel, Israel

Jonathan Robinson

4Chalmers University of Technology, Sweden, Sweden

Amit Amritkar

1University of Houston, Houston, TX, USA