Anti-GAD-associated limbic encephalitis: an unusual clinical manifestation from northwest of Ireland

Abstract

Abstract We report an unusual manifestation of anti-GAD-associated limbic encephalitis in a 59-year-old man following pacemaker insertion for cardiac pauses. Clinically, the association of anti-GAD antibody with limbic encephalitis is rare. He presented with a complex constellation of symptoms, posing a diagnostic and therapeutic challenge.

Keywords

• Anti-GAD antibody
• Limbic encephalitis
• Dysautonomia
• Seizures
• Autoimmune encephalitis