(22E,24R)-3β,5α,9α-Trihydroxyergosta-7,22-dien-6-one monohydrate

Abstract

The title ergosterol compound, C28H44O4·H2O, is composed of four fused rings (three six-membered and one five-membered) and a side chain. It is a derivative of ergosterol and was isolated from a marine-derived halotolerant fungus, Cladosporium cladosporioides PXP-49. In the crystal, molecules are assembled by classical O—H...O hydrogen bonds, forming a two-dimensional network, with base vectors [100] and [010]. The absolute configuration was assigned from the measured optical rotation and reference to the literature. An intramolecular O—H...O hydrogen bond occurs.