Imaging vesicle formation dynamics supports the flexible model of clathrin-mediated endocytosis

Tomasz J. Nawara; Yancey D. Williams; Tejeshwar C. Rao; Yuesong Hu; Elizabeth Sztul; Khalid Salaita; Alexa L. Mattheyses

doi:10.1038/s41467-022-29317-1

Nature Communications (Apr 2022)

Imaging vesicle formation dynamics supports the flexible model of clathrin-mediated endocytosis

Tomasz J. Nawara,
Yancey D. Williams,
Tejeshwar C. Rao,
Yuesong Hu,
Elizabeth Sztul,
Khalid Salaita,
Alexa L. Mattheyses

Affiliations

Tomasz J. Nawara: Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham
Yancey D. Williams: Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham
Tejeshwar C. Rao: Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham
Yuesong Hu: Department of Chemistry, Emory University
Elizabeth Sztul: Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham
Khalid Salaita: Department of Chemistry, Emory University
Alexa L. Mattheyses: Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham

DOI: https://doi.org/10.1038/s41467-022-29317-1
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 14

Abstract

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Despite decades of research, the dynamics of clathrin-coated vesicle formation is ambiguous. Here, authors use STAR microscopy to quantify the nanoscale dynamics of vesicle formation, supporting the flexible model of clathrin-mediated endocytosis.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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