Nature Communications (Nov 2022)
Seroepidemiology of enterovirus A71 infection in prospective cohort studies of children in southern China, 2013-2018
- Juan Yang,
- Qiaohong Liao,
- Kaiwei Luo,
- Fengfeng Liu,
- Yonghong Zhou,
- Gang Zou,
- Wei Huang,
- Shuanbao Yu,
- Xianglin Wei,
- Jiaxin Zhou,
- Bingbing Dai,
- Qi Qiu,
- Ralf Altmeyer,
- Hongan Hu,
- Juliette Paireau,
- Li Luo,
- Lidong Gao,
- Birgit Nikolay,
- Shixiong Hu,
- Weijia Xing,
- Peng Wu,
- H. Rogier van Doorn,
- Peter W. Horby,
- Peter Simmonds,
- Gabriel M. Leung,
- Benjamin J. Cowling,
- Simon Cauchemez,
- Hongjie Yu
Affiliations
- Juan Yang
- School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education
- Qiaohong Liao
- School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education
- Kaiwei Luo
- Hunan Provincial Center for Disease Control and Prevention (Workstation for Emerging Infectious Disease Control and Prevention, Chinese Academy of Medical Sciences)
- Fengfeng Liu
- Key Laboratory of Surveillance and Early-warning on Infectious Disease, Division of Infectious Disease, Chinese Center for Disease Control and Prevention
- Yonghong Zhou
- School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education
- Gang Zou
- Institut Pasteur of Shanghai, Chinese Academy of Sciences
- Wei Huang
- Hunan Provincial Center for Disease Control and Prevention (Workstation for Emerging Infectious Disease Control and Prevention, Chinese Academy of Medical Sciences)
- Shuanbao Yu
- Key Laboratory of Surveillance and Early-warning on Infectious Disease, Division of Infectious Disease, Chinese Center for Disease Control and Prevention
- Xianglin Wei
- School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education
- Jiaxin Zhou
- School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education
- Bingbing Dai
- Anhua County Center for Disease Control and Prevention
- Qi Qiu
- School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education
- Ralf Altmeyer
- Institut Pasteur of Shanghai, Chinese Academy of Sciences
- Hongan Hu
- Anhua County Center for Disease Control and Prevention
- Juliette Paireau
- Mathematical Modelling of Infectious Diseases Unit, Institut Pasteur, Université Paris Cité, UMR2000, CNRS
- Li Luo
- Key Laboratory of Surveillance and Early-warning on Infectious Disease, Division of Infectious Disease, Chinese Center for Disease Control and Prevention
- Lidong Gao
- Hunan Provincial Center for Disease Control and Prevention (Workstation for Emerging Infectious Disease Control and Prevention, Chinese Academy of Medical Sciences)
- Birgit Nikolay
- Mathematical Modelling of Infectious Diseases Unit, Institut Pasteur, Université Paris Cité, UMR2000, CNRS
- Shixiong Hu
- Hunan Provincial Center for Disease Control and Prevention (Workstation for Emerging Infectious Disease Control and Prevention, Chinese Academy of Medical Sciences)
- Weijia Xing
- Key Laboratory of Surveillance and Early-warning on Infectious Disease, Division of Infectious Disease, Chinese Center for Disease Control and Prevention
- Peng Wu
- WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
- H. Rogier van Doorn
- Oxford University Clinical Research Unit, Hospital for Tropical Diseases
- Peter W. Horby
- Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford
- Peter Simmonds
- Oxford University Clinical Research Unit, Hospital for Tropical Diseases
- Gabriel M. Leung
- WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
- Benjamin J. Cowling
- WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
- Simon Cauchemez
- Mathematical Modelling of Infectious Diseases Unit, Institut Pasteur, Université Paris Cité, UMR2000, CNRS
- Hongjie Yu
- School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education
- DOI
- https://doi.org/10.1038/s41467-022-34992-1
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 10
Abstract
Hand, foot and mouth disease, caused by enterovirus A71 (EV-A71) infection, is common in children in China. Here, the authors estimate EV-A71 incidence and seroprevalence using data from two longitudinal cohorts and find that, despite high infection rates, a large proportion of children under 6 are susceptible.
