D Vitamini Yetersizliği ve Depresyon: Ne Yapabiliriz?

Abstract

Vitamin D deficiency is known to be widely in Western populations. The implications of this in terms of bone health are increasingly understood, yet its impact on other health areas, particularly mental health, is unclear. Although recent data shown that vitamin D has an important impact on pathophysiology and progression of serious chronic illness, vitamin D deficiency may be common, especially in the risk groups who utilize limited sunshine such as elderly, pregnant and children. Low vitamin D levels are associated with depression, poor mood and other mental disorders. Most important data about relationship between vitamin D and depression is determination of vitamin D receptors at most area in brain and immüno reactivity of 1-alpha-hydroxylase that convert to 1.25(OH)D from 25(OH). Although there are a number of trials that have suggested a role on lower serum vitamin D level and pathophysiology of depression, more studies were need about vitamin D supplementation on treatment of depression. Vitamin D deficiency is still major public health problem for our country. Primarycare patients with a history of depression may be an important target for assessment of vitamin D levels.

Keywords

• vitamin d
• depression
• nutrition