Estimation of some Trace Elements in the Sera of People with Myocardial Infarction Disease

Abstract

Myocardial infarction is a heart problem with high risk of mortality worldwide. The epidemiological studies have shown an increase growth in the rates of cardiovascular problems globally, making this area of pathological investigations a trend to get better understanding and more clear information that help in controlling their diseases. Trace elements are dietary nutrients with very important roles in maintaining good quality of human health. Among the necessary trace elements, copper, zinc, and selenium are among the most crucial because of their roles in so many different processes throughout the body. Our goal was to determine the relationship between Cu, Zn, and Se in myocardial infarction patients, and to find their role in the disease. We have included 60 patients with myocardial disease and 30 healthy people in the study. The results have shown that Cu levels were significantly higher in myocardial infarction patients, and this would lead to raise the oxidative stress through the mediation of copper in Fenton reaction. Patients with myocardial infarction have considerably reduced levels of Zn and Se in their serum, which lowers their biological system's antioxidant ability. We suggest the use of antioxidants in diet and drugs to maintain the low risks of cardiovascular problems.

Keywords

• cardiovascular disorders
• zinc
• selenium
• copper