Case Reports in Oncology (Jul 2015)

Paraneoplastic Guillain-Barré Syndrome in Small Cell Lung Cancer

  • Moon Ho Kim,
  • Min Sik Hwang,
  • Yoon Kyoo Park,
  • Yerim Park,
  • Yong Chel Ahn,
  • Ho-Suk Oh,
  • Heui-June Ahn

DOI
https://doi.org/10.1159/000437295
Journal volume & issue
Vol. 8, no. 2
pp. 295 – 300

Abstract

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Guillain-Barré syndrome (GBS) is defined as an acute, autoimmune polyradiculoneuropathy. It is a rare disease that occurs at a rate of 1.11 cases per 100,000 person-years. However, once infected, up to 20% of patients develop severe disability, and approximately 5% die. There have been reports of GBS in different cancers. Among them, there are 6 previous reports of GBS in small cell lung cancer. Here, we report a case of a 52-year-old man who was diagnosed with GBS in the setting of small cell lung cancer with chemotherapy.

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