Toxics (Jun 2014)

The Alchemist’s Approach to Metal Poisoning: Transforming the Metal Burden

  • Wayne Briner

DOI
https://doi.org/10.3390/toxics2030364
Journal volume & issue
Vol. 2, no. 3
pp. 364 – 376

Abstract

Read online

Metal poisoning is a global problem with humans being exposed to a wide range of metals in varying doses and varying time frames. Traditionally, treatment involves removal of the toxic source or chelation therapy. An intermediate approach is needed. This review outlines the argument for the use of essential metal supplementation as a strategy to induce metallothionein expression and displace the toxic metal from important biological systems, improving the metal burden of the patient. Specific recommendations are given for supplementation with calcium, zinc and vitamin E as a broad strategy to improve the status of those exposed to toxic metals.

Keywords