Медицинский совет (Dec 2015)

Experience with a multi-strain probiotic in infants with functional gastrointestinal disorders

  • I. N. Zakharova,
  • N. G. Sugyan,
  • M. D. Ardatskaya,
  • S. I. Lazareva

DOI
https://doi.org/10.21518/2079-701X-2015-14-48-53
Journal volume & issue
Vol. 0, no. 14
pp. 48 – 53

Abstract

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In 90% of infants, the introduction of complementary foods or transition to bottle or mixed feeding is characterized by changes in the frequency and type of stool, intestinal colic, regurgitation, flatulence. Administration of the multi-strain probiotic Bac-Set Baby for 14 days in infants with FGID allows to manage the changes in the frequency and type of stool in 80% of cases, symptoms of intestinal colic in 86% of children, regurgitation in 70%, and flatulence in 78% of children. Studies of the metabolic activity of obligate intestinal microorganisms demonstrated that multi-strain probiotic Bac-Set Baby (Probiotics International Ltd., UK) in children with FGID is effective in the management and restoration of the intestinal microbiota in children in the first year of life. The administration was associated with a tendency to restore the activity of the colonic obligate microflora, particularly bifido- and lactobacteria, due to changes in the qualitative composition of microorganisms characterized by reduced activity of facultative and residual anaerobic (in type 1) and aerobic (in type 2) microfloras, and improvement of the intraluminal environment. In addition, there was a tendency toward normalization of proteolysis and elimination of residual (opportunistic) microorganisms as a result of treatment.

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