Diagnostics (Feb 2023)

Multi-Contrast Differentiation by Dual-Energy Spectral CT Angiography in a Patient with Pulmonary Barium Granulomas

  • Tommaso D’Angelo,
  • Francesco M. Arico,
  • Lydia Broccio,
  • Giorgio Ascenti,
  • Silvio Mazziotti,
  • Christian Booz,
  • Simon S. Martin,
  • Ibrahim Yel,
  • Ludovica R. M. Lanzafame,
  • Alfredo Blandino,
  • Carmelo Sofia

DOI
https://doi.org/10.3390/diagnostics13050832
Journal volume & issue
Vol. 13, no. 5
p. 832

Abstract

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Barium inhalation usually relates to accidental aspiration during radiological procedures with an oral contrast agent. When present, barium lung deposits are visible as high-density opacities on chest X-ray or CT scan due to high atomic number, and they may be indistinguishable from calcifications. Dual-layer spectral CT has shown good material differentiation capabilities, due to its increased high-Z element range and smaller spectral separation between low- and high-energy spectral data. We present the case of a 17-year-old female with a history of tracheoesophageal fistula, who underwent chest CT angiography on a dual-layer spectral platform. Despite the close Z numbers and K-edge energy levels of the two different contrast materials, spectral CT was able to identify barium lung deposits from a previous swallowing study and to clearly distinguish them from calcium and the surrounding iodine-containing structures.

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