World Journal of Emergency Surgery (Jan 2018)
Raising concerns about the Sepsis-3 definitions
- Massimo Sartelli,
- Yoram Kluger,
- Luca Ansaloni,
- Timothy C. Hardcastle,
- Jordi Rello,
- Richard R. Watkins,
- Matteo Bassetti,
- Eleni Giamarellou,
- Federico Coccolini,
- Fikri M. Abu-Zidan,
- Abdulrashid K. Adesunkanmi,
- Goran Augustin,
- Gian L. Baiocchi,
- Miklosh Bala,
- Oussema Baraket,
- Marcelo A. Beltran,
- Asri Che Jusoh,
- Zaza Demetrashvili,
- Belinda De Simone,
- Hamilton P. de Souza,
- Yunfeng Cui,
- R. Justin Davies,
- Sameer Dhingra,
- Jose J. Diaz,
- Salomone Di Saverio,
- Agron Dogjani,
- Mutasim M. Elmangory,
- Mushira A. Enani,
- Paula Ferrada,
- Gustavo P. Fraga,
- Sabrina Frattima,
- Wagih Ghnnam,
- Carlos A. Gomes,
- Souha S. Kanj,
- Aleksandar Karamarkovic,
- Jakub Kenig,
- Faryal Khamis,
- Vladimir Khokha,
- Kaoru Koike,
- Kenneth Y. Y. Kok,
- Arda Isik,
- Francesco M. Labricciosa,
- Rifat Latifi,
- Jae G. Lee,
- Andrey Litvin,
- Gustavo M. Machain,
- Ramiro Manzano-Nunez,
- Piotr Major,
- Sanjay Marwah,
- Michael McFarlane,
- Ziad A. Memish,
- Cristian Mesina,
- Ernest E. Moore,
- Frederick A. Moore,
- Noel Naidoo,
- Ionut Negoi,
- Richard Ofori-Asenso,
- Iyiade Olaoye,
- Carlos A. Ordoñez,
- Mouaqit Ouadii,
- Ciro Paolillo,
- Edoardo Picetti,
- Tadeja Pintar,
- Alfredo Ponce-de-Leon,
- Guntars Pupelis,
- Tarcisio Reis,
- Boris Sakakushev,
- Hossein Samadi Kafil,
- Norio Sato,
- Jay N. Shah,
- Boonying Siribumrungwong,
- Peep Talving,
- Cristian Tranà,
- Jan Ulrych,
- Kuo-Ching Yuan,
- Fausto Catena
Affiliations
- Massimo Sartelli
- Department of Surgery, Macerata Hospital
- Yoram Kluger
- Department of General Surgery, Division of Surgery, Rambam Health Care Campus
- Luca Ansaloni
- General Surgery Department, Bufalini Hospital
- Timothy C. Hardcastle
- Trauma Service, Inkosi Albert Luthuli Central Hospital
- Jordi Rello
- Department of Clinical Research & Innovation in Pneumonia and Sepsis, Vall d’Hebron Institute of Research (VHIR)
- Richard R. Watkins
- Division of Infectious Diseases, Cleveland Clinic Akron General
- Matteo Bassetti
- Infectious Diseases Division, Santa Maria Misericordia University Hospital
- Eleni Giamarellou
- 6th Department of Internal Medicine, Hygeia General Hospital
- Federico Coccolini
- General Surgery Department, Bufalini Hospital
- Fikri M. Abu-Zidan
- Department of Surgery, College of Medicine and Health Sciences, UAE University
- Abdulrashid K. Adesunkanmi
- Department of Surgery, College of Health Sciences, Obafemi Awolowo University
- Goran Augustin
- Department of Surgery, University Hospital Centre
- Gian L. Baiocchi
- Department of Clinical and Experimental Sciences, University of Brescia
- Miklosh Bala
- Trauma and Acute Care Surgery Unit, Hadassah Hebrew University Medical Center
- Oussema Baraket
- Department of Surgery, Bizerte Hospital
- Marcelo A. Beltran
- Department of General Surgery, Hospital San Juan de Dios de La Serena
- Asri Che Jusoh
- Department of General Surgery, Kuala Krai Hospital
- Zaza Demetrashvili
- Department General Surgery, Kipshidze Central University Hospital
- Belinda De Simone
- Department of Digestive Surgery, Cannes Hospital
- Hamilton P. de Souza
- Department of Surgery, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
- Yunfeng Cui
- Department of Surgery, Tianjin Nankai Hospital, Nankai Clinical School of Medicine, Tianjin Medical University
- R. Justin Davies
- Colorectal Unit, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust
- Sameer Dhingra
- School of Pharmacy, Faculty of Medical Sciences, The University of the West Indies
- Jose J. Diaz
- Division of Acute Care Surgery, Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland
- Salomone Di Saverio
- Colorectal Unit, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust
- Agron Dogjani
- Department of Surgery, University Hospital of Trauma
- Mutasim M. Elmangory
- Sudan National Public Health Laboratory, Federal Ministry of Health
- Mushira A. Enani
- Department of Medicine, Infectious Disease Division, King Fahad Medical City
- Paula Ferrada
- Department of Surgery, Virginia Commonwealth University
- Gustavo P. Fraga
- Division of Trauma Surgery, Department of Surgery, School of Medical Sciences, University of Campinas (Unicamp)
- Sabrina Frattima
- Istituto Clinico San Rocco di Franciacorta
- Wagih Ghnnam
- Department of General Surgery, Mansoura Faculty of Medicine, Mansoura University
- Carlos A. Gomes
- Department of Surgery, Hospital Universitário Terezinha de Jesus, Faculdade de Ciências Médicas e da Saúde de Juiz de Fora
- Souha S. Kanj
- Division of Infectious Diseases, Department of Internal Medicine, American University of Beirut
- Aleksandar Karamarkovic
- Clinic for Emergency Surgery, Medical Faculty, University of Belgrade
- Jakub Kenig
- Third Department of General Surgery, Jagiellonian University Medical College
- Faryal Khamis
- Department of Internal Medicine, Royal Hospital
- Vladimir Khokha
- Department of Emergency Surgery, City Hospital
- Kaoru Koike
- Department of Primary Care and Emergency Medicine, Graduate School of Medicine, Kyoto University
- Kenneth Y. Y. Kok
- Department of Surgery, The Brunei Cancer Centre
- Arda Isik
- Department of General Surgery, Faculty of Medicine, Erzincan University
- Francesco M. Labricciosa
- Global Alliance for Infections in Surgery
- Rifat Latifi
- Department of Surgery, Division of Trauma, University of Arizona
- Jae G. Lee
- Department of Surgery, College of Medicine, Yonsei University
- Andrey Litvin
- Surgical Disciplines, Immanuel Kant Baltic Federal University/Regional Clinical Hospital
- Gustavo M. Machain
- Department of Surgery, Universidad Nacional de Asuncion
- Ramiro Manzano-Nunez
- Clinical Research Center, Fundacion Valle del Lili
- Piotr Major
- 2nd Department of General Surgery, Jagiellonian University Medical College
- Sanjay Marwah
- Department of Surgery, Post-Graduate Institute of Medical Sciences
- Michael McFarlane
- Department of Surgery, Radiology, University Hospital of the West Indies
- Ziad A. Memish
- Infectious Diseases Division, Department of Medicine, Prince Mohamed Bin Abdulaziz Hospital, Ministry of Health
- Cristian Mesina
- Second Surgical Clinic, Emergency Hospital of Craiova
- Ernest E. Moore
- Department of Surgery, Denver Health Medical Center, University of Colorado
- Frederick A. Moore
- Department of Surgery, Division of Acute Care Surgery, and Center for Sepsis and Critical Illness Research, College of Medicine, University of Florida
- Noel Naidoo
- Department of Surgery, University of KwaZulu-Natal
- Ionut Negoi
- Department of Surgery, Emergency Hospital of Bucharest
- Richard Ofori-Asenso
- Research Unit, Health Policy Consult
- Iyiade Olaoye
- Department of Surgery, University of Ilorin, Teaching Hospital
- Carlos A. Ordoñez
- Department of Surgery and Critical Care, Universidad del Valle, Fundación Valle del Lili
- Mouaqit Ouadii
- Department of Surgery, Hassan II University Hospital, Medical School of Fez, Sidi Mohamed Benabdellah University
- Ciro Paolillo
- Department of Emergency Medicine, Santa Maria Misericordia University Hospital
- Edoardo Picetti
- Department of Anesthesia and Intensive Care, Azienda Ospedaliero-Universitaria Parma
- Tadeja Pintar
- Department of Surgery, UMC Ljubljana
- Alfredo Ponce-de-Leon
- Laboratory of Clinical Microbiology, Department of Infectious Diseases, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
- Guntars Pupelis
- Department of General and Emergency Surgery, Riga East University Hospital “Gailezers”
- Tarcisio Reis
- Emergency Post-Operative Department, Otavio De Freitas Hospital
- Boris Sakakushev
- General Surgery Department, Medical University, University Hospital St George
- Hossein Samadi Kafil
- Drug Applied Research Center, Tabriz University of Medical Sciences
- Norio Sato
- Department of Aeromedical Services for Emergency and Trauma Care, Graduate School of Medicine, Ehime University
- Jay N. Shah
- Department of Surgery, Patan Hospital, Patan Academy of Health Sciences Lalitpur
- Boonying Siribumrungwong
- Department of Surgery, Faculty of Medicine, Thammasat University Hospital, Thammasat University
- Peep Talving
- Department of Surgery, North Estonia Medical Center
- Cristian Tranà
- Department of Surgery, Macerata Hospital
- Jan Ulrych
- First Department of Surgery, First Faculty of Medicine, Charles University in Prague
- Kuo-Ching Yuan
- Department of Emergency and Critical Care Medicine, Taipei Medical University Hospital
- Fausto Catena
- Department of Emergency Surgery, Parma Maggiore Hospital
- DOI
- https://doi.org/10.1186/s13017-018-0165-6
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 9
Abstract
Abstract The Global Alliance for Infections in Surgery appreciates the great effort of the task force who derived and validated the Sepsis-3 definitions and considers the new definitions an important step forward in the evolution of our understanding of sepsis. Nevertheless, more than a year after their publication, we have a few concerns regarding the use of the Sepsis-3 definitions.
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