Therapies and outcomes following extramedullary relapse of pediatric and young adult ALL after CD19 CAR T-cell therapy

• Barbara D. Friedes,
• Amanda M. DiNofia,
• Emma Iannone,
• Yimei Li,
• Susan R. Rheingold,
• Allison Barz Leahy,
• Lisa Wray,
• Colleen Callahan,
• Diane Baniewicz,
• Lauren Vernau,
• Kelly D. Getz,
• Richard Aplenc,
• Shannon L. Maude,
• Stephan A. Grupp,
• Regina M. Myers

Affiliations

Barbara D. Friedes

Department of Pediatrics, Children’s Hospital of Philadelphia, Philadelphia, PA

Amanda M. DiNofia

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

Emma Iannone

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA; University of Colorado School of Medicine, Aurora, CO

Yimei Li

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA; University of Colorado School of Medicine, Aurora, CO; Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia, PA

Susan R. Rheingold

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

Allison Barz Leahy

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

Lisa Wray

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

Colleen Callahan

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA

Diane Baniewicz

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA

Lauren Vernau

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA

Kelly D. Getz

Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

Richard Aplenc

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

Shannon L. Maude

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

Stephan A. Grupp

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

Regina M. Myers

Division of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; Correspondence: Regina M. Myers, Children’s Hospital of Philadelphia, Hub for Clinical Collaboration, Office 3545, 3500 Civic Center Blvd, Philadelphia, PA 19104;