Emerging Infectious Diseases (Sep 2019)

Vaccine Effectiveness against DS-1–Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013–2015

  • Khuzwayo C. Jere,
  • Naor Bar-Zeev,
  • Adams Chande,
  • Aisleen Bennett,
  • Louisa Pollock,
  • Pedro F. Sanchez-Lopez,
  • Osamu Nakagomi,
  • Jacqueline E. Tate,
  • Umesh D. Parashar,
  • Robert S. Heyderman,
  • Neil French,
  • Miren Iturriza-Gomara,
  • Nigel A. Cunliffe

DOI
https://doi.org/10.3201/eid2509.190258
Journal volume & issue
Vol. 25, no. 9
pp. 1734 – 1737

Abstract

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Atypical DS-1–like G1P[8] rotaviruses emerged in 2013 in Malawi after rotavirus vaccine introduction. Vaccine effectiveness among infants hospitalized with acute DS-1–like G1P[8] rotavirus gastroenteritis was 85.6% (95% CI 34.4%–96.8%). These findings suggest that vaccine provides protection against these strains despite their emergence coinciding with vaccine introduction.

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