Forgotten coindex of some non-toxic dendrimers structure used in targeted drug delivery

Abstract

In recent past, porphyrin-based dendrimers have gained great attraction due to their usefulness in nano devices and photo-dynamic therapy. New technologies based upon nano-materials or dendrimers have potential to overcome the problems due to conventional drug delivery, like toxicity, poor solubility and poor release pattern of drugs. The chemical and physical properties of these highly branched nanometer sized dendrimers depend on their structure. In chemical network theory, various topological indices are used to predict chemical properties of molecules(dendrimers). Among many useful topological descriptors forgotten coindex is relatively less explored but is found very useful in material engineering, pharmaceutical and chemical industries. In this article, we consider some special dendrimers, like poly(propyl) ether imine, porphyrin, and zinc-porphyrin, and nanostars like D1[k] and D2[k] and compute forgotten coindex for these important structures.

Keywords

• topological descriptors
• forgotten coindex
• nanostar dendrimers
• poly(propyl) ether imine
• porphyrin and zinc–porphyrin dendrimers