BIOSPECIFIC HEMOSORBENTS. THE SUCCESSES AND PROBLEMS

Abstract

Understanding the leading role of the endogenous proteolysis activation in a number of serious diseases has existed for a long time, the large group of antifermental drugs has been created and widely used. The hemosorbent, capable of selectively removing from the blood the most significant class of serine proteases in purulent septic pathology, was developed and tested in the clinic. The nature of the hemosorbents` therapeutic effect and the status of the proteins metabolism certain parts in connection with the application for haemosorption with biospecific antiproteinase hemosorbents has been studied in patients with diffuse purulent peritonitis of appendicular origin.

Keywords

• hemosorbent
• peritonitis
• appendicitis
• antiproteinase hemosorbent
• detoxification