Nature Communications (Dec 2022)

Limited conservation in cross-species comparison of GLK transcription factor binding suggested wide-spread cistrome divergence

  • Xiaoyu Tu,
  • Sibo Ren,
  • Wei Shen,
  • Jianjian Li,
  • Yuxiang Li,
  • Chuanshun Li,
  • Yangmeihui Li,
  • Zhanxiang Zong,
  • Weibo Xie,
  • Donald Grierson,
  • Zhangjun Fei,
  • Jim Giovannoni,
  • Pinghua Li,
  • Silin Zhong

DOI
https://doi.org/10.1038/s41467-022-35438-4
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 12

Abstract

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Unlike microbes and mammals, cistrome dynamics in plants remains unclear. Here, using GOLDEN2-LIKE (GLK) transcription factor as an example, the authors find that most GLK binding sites are species-specific and the binding divergence is caused by cis-variations through inter-species transformation experiment.