PLoS ONE (Jan 2024)

Cardiac magnetic resonance imaging in repaired tetralogy of Fallot: A longitudinal midterm follow-up study.

  • Golnaz Houshmand,
  • Rahem Rahmati,
  • Elahe Meftah,
  • Fatemeh Zarimeidani,
  • Mohammadrafi Khorgami,
  • Seyyed Mojtaba Ghorashi,
  • Amir Fazeli,
  • Negar Omidi,
  • Sedigheh Saedi,
  • Marzieh Motevalli,
  • Majid Maleki,
  • Hamidreza Pouraliakbar

DOI
https://doi.org/10.1371/journal.pone.0308362
Journal volume & issue
Vol. 19, no. 12
p. e0308362

Abstract

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BackgroundBiventricular dysfunction is frequent in patients with repaired tetralogy of Fallot, necessitating routine imaging to monitor for worsening conditions and determine whether procedures like pulmonary valve replacement (PVR) are needed. This study aimed to highlight the parameters of cardiac magnetic resonance imaging (CMR) and their association with adverse outcomes in the midterm follow-up of these patients.MethodsThis longitudinal study recruited all patients with a history of tetralogy of Fallot total correction (TFTC) who had two CMR images at a minimum three-month interval at Rajaie Center from 2007 through 2017.ResultsFifty-six patients at a mean age of 15.23 ± 11.66 years at TFTC and a 1:1 gender distribution were assessed. Regarding adverse events, PVR was done on 18 patients (32%). Right and left ventricular dysfunction occurred in 43 (76.8%) and 18 (32.1%) patients, respectively. Death did not occur in the present study. RVOT fibrosis was present in 47 (92.2%). The stroke volume of both ventricles increased during the follow-up (P ConclusionMyocardial strain and ventriculoarterial coupling parameters could underscore personalized-approached therapy and follow-up to improve outcomes.