Journal of Biological Research (May 2024)

RAT SERUM IMPROVES RAT PSEUDOISLET FORMATION AND INSULIN GENE EXPRESSION

  • L. Lione,
  • A. Puddu,
  • A. Pedemonte,
  • G.L. Viviani

DOI
https://doi.org/10.4081/jbr.2001.12502
Journal volume & issue
Vol. 77, no. 1-3

Abstract

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Langerhana islets are constituted by four different cellular populations with a central core of  cells surrounded by ,  and PP cells. Islets may be dissociated to single component cells that re-establish contacts to form organized and functional aggregates capable of responding appropriately to islet secretory stimuli (1-5). [...]