CDK2 and CDK4: Cell Cycle Functions Evolve Distinct, Catalysis-Competent Conformations, Offering Drug Targets

• Wengang Zhang,
• Yonglan Liu,
• Hyunbum Jang,
• Ruth Nussinov

Affiliations

Wengang Zhang

Cancer Innovation Laboratory, National Cancer Institute, Frederick, Maryland, United States

Yonglan Liu

Cancer Innovation Laboratory, National Cancer Institute, Frederick, Maryland, United States

Hyunbum Jang

Computational Structural Biology Section, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States

Ruth Nussinov

Computational Structural Biology Section, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States