PLoS Computational Biology (Jun 2023)

HAT: Hypergraph analysis toolbox.

  • Joshua Pickard,
  • Can Chen,
  • Rahmy Salman,
  • Cooper Stansbury,
  • Sion Kim,
  • Amit Surana,
  • Anthony Bloch,
  • Indika Rajapakse

DOI
https://doi.org/10.1371/journal.pcbi.1011190
Journal volume & issue
Vol. 19, no. 6
p. e1011190

Abstract

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Recent advances in biological technologies, such as multi-way chromosome conformation capture (3C), require development of methods for analysis of multi-way interactions. Hypergraphs are mathematically tractable objects that can be utilized to precisely represent and analyze multi-way interactions. Here we present the Hypergraph Analysis Toolbox (HAT), a software package for visualization and analysis of multi-way interactions in complex systems.