A Breath of Fresh Air: BCG Prevents Adult Pulmonary Tuberculosis

Abstract

Objectives: The efficacy of childhood BCG vaccination in the prevention of adult pulmonary tuberculosis is not universally accepted. Methods: We reviewed the published literature and summarized studies of BCG vaccination reporting long-term protection against pulmonary TB. Results: We identified 15 papers reporting prospective studies and their long-term follow up, retrospective studies or systematic reviews. Conclusions: Good quality evidence supports the efficacy of BCG vaccination in the prevention of adult pulmonary tuberculosis. Keywords: tuberculosis, BCG, vaccine