ACS Omega
(Oct 2021)
Scalable Biosynthetic Production of Knotted Peptides Enables ADME and Thermodynamic Folding Studies
- Christopher J. Schwalen,
- Charles Babu,
- Swastik Phulera,
- Qin Hao,
- Daniel Wall,
- David O. Nettleton,
- Tejas P. Pathak,
- Piro Siuti
Affiliations
- Christopher J. Schwalen
- Global Discovery Chemistry, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States
- Charles Babu
- Global Discovery Chemistry, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States
- Swastik Phulera
- Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States
- Qin Hao
- Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States
- Daniel Wall
- Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States
- David O. Nettleton
- Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States
- Tejas P. Pathak
- Global Discovery Chemistry, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States
- Piro Siuti
- Global Discovery Chemistry, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States
- DOI
-
https://doi.org/10.1021/acsomega.1c03707
- Journal volume & issue
-
Vol. 6,
no. 44
pp.
29555
– 29566
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