In the tradition of studies about central places theory in urban Systems, some contributions have emphasized the invariability of the concentration index in Systems of a certain size, that comply with one of the main organizing principles elucidated by W. Christaller. This research of the structural change is an empirical, longitudinal study of some Swiss representative regions(1850-1990), their transformation of agricultural land into industrial and urban-industrial territoriality, and a prevision of their future.Central places, hierarchical structure, Swiss urban System.