Results in Chemistry (Dec 2023)

Polymeric nanoparticles approach and identification and characterization of novel biomarkers for colon cancer

  • Devesh u kapoor,
  • Rahul Garg,
  • Mansi Gaur,
  • Bhupendra G. Prajapati,
  • Gyan Agrawal,
  • Sankha Bhattacharya,
  • Gehan M. Elossaily

Journal volume & issue
Vol. 6
p. 101167

Abstract

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The need for novel approaches to the treatment of colon cancer, a common and deadly disease, is universal. In this compilation, we look at how polymeric nanoparticles (Polymeric nanoparticles) could be used to treat colon cancer. Advantages of Polymeric nanoparticles in Fig.hting this disease include targeted medication administration, enhanced therapy efficacy, and fewer adverse effects. Their impact on cancer treatment is huge. Drug release and miRNA play crucial roles in this struggle by enabling early disease identification, individualised treatment strategies, and bolstering PONP mechanisms. The most up-to-date developments in the use of biomarkers in the diagnosis and prognosis of colon cancer are also discussed. Biomarkers used in toxicology range from genes to epigenomes to molecules. Better patient outcomes can be expected when biomarkers are used in conjunction with Polymeric nanoparticles for personalised treatment and cytotoxicity assessment. This strategy has the potential to completely transform cancer care by putting the needs of each patient first. Combining therapeutic and diagnostic capabilities inside a single nanoparticle system, the use of drug delivery and miRNA elevates the concept of theranostic applications employing Polymeric nanoparticles in colon cancer. This novel method enables toxicological and diagnostic capabilities to visualise and monitor colon cancer treatment with tailored drug administration. Additional research and clinical validation are necessary to implement these developments in clinical practise. There is reason to be optimistic about the future of cancer therapy when Polymeric nanoparticles are used in conjunction with standard medical care.

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