Nature Communications (Dec 2019)

Cerebral oxygenation during locomotion is modulated by respiration

  • Qingguang Zhang,
  • Morgane Roche,
  • Kyle W. Gheres,
  • Emmanuelle Chaigneau,
  • Ravi T. Kedarasetti,
  • William D. Haselden,
  • Serge Charpak,
  • Patrick J. Drew

DOI
https://doi.org/10.1038/s41467-019-13523-5
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 15

Abstract

Read online

Understanding mechanisms of cerebral oxygen regulation is critical for healthy brain function. Here the authors show that respiration is a key modulator of cerebral oxygenation, which will be helpful in better resolving neurally-generated functional brain imaging signals, such as BOLD fMRI.