Frontiers in Surgery (Jun 2025)

Anticipating postoperative complications in hepatobiliary surgery: procalcitonine as predictive factor

  • Shouwen Zhao,
  • Yuanyuan Song,
  • Le Zhang,
  • Sunan Shi,
  • Jie Li,
  • Yuping Ma,
  • Yong Liao,
  • Zhongguang Zhen

DOI
https://doi.org/10.3389/fsurg.2025.1564843
Journal volume & issue
Vol. 12

Abstract

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Background and aimsFew studies have indicated that procalcitonin has a potential role in anticipating postoperative complications of hepatic surgery. Here, we focused on validating the relationship between posthepatectomy and serum procalcitonin as short-term prognostic factors.MethodsData from 52 patients who underwent hepatectomy (partial) due to hepatocellular carcinoma from June 2018 to July 2023 were enrolled to evaluate the risk factors related to post-hepatectomy complications, especially post-hepatectomy liver failure and 30-day survival.Results52 patients were included in the study, and their data was analyzed for PCT. 21 showed raised PCT (>1 ng/ml). Results showed a significant association of PCT with post-hepatectomy liver failure, and the same is associated with 30-day mortality in ICU-admitted patients.ConclusionElevated PCT levels in patients after hepatic surgery are associated with poor prognosis and could be used as a potential predictive factor.

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