Paula Coutinho’s outstanding contribution to the definition of Machado-Joseph disease

Abstract

ABSTRACT Machado-Joseph disease, also known as spinocerebellar ataxia type 3, is the most common form of autosomal dominant ataxia in the world. Paula Coutinho, a highly-regarded Portuguese neurologist worldwide, had a seminal participation in the definition of this disease, more than 40 years ago.

Keywords

• ataxia
• ataxias espinocerebelares
• doença de Machado-Joseph
• neurologia
• história