Communications Biology (Apr 2022)
Structure-based inhibitor design for reshaping bacterial morphology
- Yuri Choi,
- Ji Su Park,
- Jinshil Kim,
- Kyungjin Min,
- Kiran Mahasenan,
- Choon Kim,
- Hye-Jin Yoon,
- Sewon Lim,
- Dae Hee Cheon,
- Yan Lee,
- Sangryeol Ryu,
- Shahriar Mobashery,
- B. Moon Kim,
- Hyung Ho Lee
Affiliations
- Yuri Choi
- Department of Chemistry, College of Natural Sciences, Seoul National University
- Ji Su Park
- Department of Chemistry, College of Natural Sciences, Seoul National University
- Jinshil Kim
- Department of Food and Animal Biotechnology, Department of Agricultural Biotechnology, Research Institute for Agriculture and Life Sciences, Seoul National University
- Kyungjin Min
- Department of Chemistry, College of Natural Sciences, Seoul National University
- Kiran Mahasenan
- Department of Chemistry and Biochemistry, University of Notre Dame
- Choon Kim
- Department of Chemistry and Biochemistry, University of Notre Dame
- Hye-Jin Yoon
- Department of Chemistry, College of Natural Sciences, Seoul National University
- Sewon Lim
- Department of Chemistry, College of Natural Sciences, Seoul National University
- Dae Hee Cheon
- Department of Chemistry, College of Natural Sciences, Seoul National University
- Yan Lee
- Department of Chemistry, College of Natural Sciences, Seoul National University
- Sangryeol Ryu
- Department of Food and Animal Biotechnology, Department of Agricultural Biotechnology, Research Institute for Agriculture and Life Sciences, Seoul National University
- Shahriar Mobashery
- Department of Chemistry and Biochemistry, University of Notre Dame
- B. Moon Kim
- Department of Chemistry, College of Natural Sciences, Seoul National University
- Hyung Ho Lee
- Department of Chemistry, College of Natural Sciences, Seoul National University
- DOI
- https://doi.org/10.1038/s42003-022-03355-3
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 10
Abstract
Peptidoglycan hydrolase 3 (Pgp3) inhibitors are designed that can change the helical morphology of Campylobacter jejuni to rod-shaped and decrease its virulence.
