N-terminal natriuretic propeptide in diagnostics of myocardial injuries after coronary artery bypass grafting on a beating heart

Abstract

Dynamics of N-terminal natriuretic propeptide (NT-proBNP) and troponin T in the blood of patients with ischemic heart disease after CABG on a beating heart is studied. It is found out that the level of NT-proBNP in patients with ischemic heart disease at admission correlates with their functional class, left ventricular ejection fraction and end-diastolic volume). It is also shown that the level of NT-proBNP increases in 1 day after CABG and reaches the maximum values in3 days. At the 15th day a decrease in the level of NT-proBNP is observed, however, which reaches the baseline values. The analysis of correlation between NT-proBNP and troponin Т has revealed an inverse correlation between the indicators under study, which testifies to the fact that NT-proBNP cannot be used as a myocardial injury marker in patients with ischemic heart disease after CABG.

Keywords

• ИШЕМИЧЕСКАЯ БОЛЕЗНЬ СЕРДЦА
• КОРОНАРНОЕ ШУНТИРОВАНИЕ
• МАРКЕРЫ ПОВРЕЖДЕНИЯ МИОКАРДА
• ТРОПОНИН Т
• N-ТЕРМИНАЛЬНЫЙ МОЗГОВОЙ НАТРИЙУРЕТИЧЕСКИЙ ПРОПЕПТИД