Frontiers in Pediatrics (Sep 2022)

Designing a Visit Schedule for Longitudinal Studies in Pediatric Research

  • Steven Hirschfeld,
  • Michael Dellarco,
  • Cindy J. Nowinski,
  • Jerry Slotkin

DOI
https://doi.org/10.3389/fped.2022.883994
Journal volume & issue
Vol. 10

Abstract

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A challenge for longitudinal studies is combining individual assessments into visits that are scientifically logical, not burdensome for participants, well-choreographed, and operationally feasible. The visits then need to be sequenced and spaced to address the scientific goals and generate a data archive that is sufficiently robust and well-documented to support subsequent analyses. This paper summarizes comprehensive multi-disciplinary activities that were coordinated to design the content, format, and structure of the National Children's Study and concurrently serve as a model and resource for other studies.

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