European Journal of Medical Research (Sep 2021)
Thrombin-activated platelet-rich plasma enhances osteogenic differentiation of human periodontal ligament stem cells by activating SIRT1-mediated autophagy
Abstract
Highlights 1. PRP enhances cell viability and osteogenic differentiation of hPDLSCs. 2. Activated PRP dose-dependently increases cell autophagy. 3. Inhibition of autophagy abrogates PRP-induced osteogenic differentiation of hPDLSCs.
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