Molecules (Mar 2000)

Synthesis and Physicochemical Study of a Quinoxaline Derivative with Potencial Antineoplasic or Anti-HIV Activity

  • Gabriela A. Rodrigo,
  • Diana G. Bekerman,
  • Adriana E. Robinsohn,
  • Beatriz M. Fernández

DOI
https://doi.org/10.3390/50300358
Journal volume & issue
Vol. 5, no. 3
pp. 358 – 359

Abstract

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Kinetics of the synthesis of 3-[3-quinoxaline(1H)-one]propionic acid (I) were performed. This compound was achieved from reaction between o-phenylenediamine and α-ketoglutaric acid under different experimental conditions, and it was sent to the National Cancer Institute (USA) for its pharmacological evaluation.

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