Urology Case Reports (Mar 2024)

A case report of aggressive mixed epithelial and stromal tumor of the kidney with malignant transformation

  • Anahita Ansari Djafari,
  • Hossein Rahnama,
  • Babak Javanmard,
  • Seyyed Ali Hojjati,
  • Sareh Salarinejad

Journal volume & issue
Vol. 53
p. 102689

Abstract

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Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare benign kidney tumor. In rare cases, malignant transformation, such as sarcomatoid features indicates poor clinical outcomes.In this study, we will describe a 45 years old man with a diagnosis of MESTK with malignant transformation of the sarcomatoid component, after right radical nephrectomy. The patient underwent chemotherapy with adriamycin, ifosfamide, and granulocyte-colony stimulating factor (G-CSF).The radiological characteristics of MESTK can pose diagnostic challenges due to its non-unique radiological appearance. The presence of sarcomatoid transformation is a hallmark feature of malignant MESTK which can be very aggressive.

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