Tumor attachment to Major intrahepatic vascular for Colorectal liver metastases
Wei Liu,
Yong Cui,
Xiao-Gang Wu,
Feng-Lin Chen,
Kun Wang,
Ying-Shi Sun,
Bao-Cai Xing
Affiliations
Wei Liu
Hepatopancreatobiliary Surgery Department I, Beijing Cancer Hospital and Institute, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University School of Oncology
Yong Cui
Department of Radiology, Peking University School of Oncology, Beijing Cancer Hospital and Institute, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education
Xiao-Gang Wu
Hepatopancreatobiliary Surgery Department I, Beijing Cancer Hospital and Institute, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University School of Oncology
Feng-Lin Chen
Hepatopancreatobiliary Surgery Department I, Beijing Cancer Hospital and Institute, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University School of Oncology
Kun Wang
Hepatopancreatobiliary Surgery Department I, Beijing Cancer Hospital and Institute, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University School of Oncology
Ying-Shi Sun
Department of Radiology, Peking University School of Oncology, Beijing Cancer Hospital and Institute, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education
Bao-Cai Xing
Hepatopancreatobiliary Surgery Department I, Beijing Cancer Hospital and Institute, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University School of Oncology
Abstract Background Colorectal liver metastases attached major intrahepatic vessels has been considered to be a risk factor for survival outcome after liver resection. The present study aimed to clarify the outcomes of R1 surgery (margin 4 cycles, clinical risk score 3–5, RAS mutation, parenchymal R1 and CA199 > 100 IU/ml were identified as independent predictive factors of overall survival (p < 0.05). There was no significant difference for local recurrence among three groups. Conclusion Parenchymal R1 resection was independent risk factor for CRLM. Vascular R1 surgery achieved survival outcomes equivalent to R0 resection. Non-anatomic liver resection for CRLM attached to intrahepatic vessels might be pursued to increase patient resectability by preoperative chemotherapy.
