Nature Communications (Apr 2021)
Incidence and predictive biomarkers of Clostridioides difficile infection in hospitalized patients receiving broad-spectrum antibiotics
- Cornelis H. van Werkhoven,
- Annie Ducher,
- Matilda Berkell,
- Mohamed Mysara,
- Christine Lammens,
- Julian Torre-Cisneros,
- Jesús Rodríguez-Baño,
- Delia Herghea,
- Oliver A. Cornely,
- Lena M. Biehl,
- Louis Bernard,
- M. Angeles Dominguez-Luzon,
- Sofia Maraki,
- Olivier Barraud,
- Maria Nica,
- Nathalie Jazmati,
- Frederique Sablier-Gallis,
- Jean de Gunzburg,
- France Mentré,
- Surbhi Malhotra-Kumar,
- Marc J. M. Bonten,
- Maria J. G. T. Vehreschild,
- the ANTICIPATE Study Group
Affiliations
- Cornelis H. van Werkhoven
- Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University
- Annie Ducher
- Da Volterra
- Matilda Berkell
- Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, University of Antwerp
- Mohamed Mysara
- Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, University of Antwerp
- Christine Lammens
- Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, University of Antwerp
- Julian Torre-Cisneros
- Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba (UCO)
- Jesús Rodríguez-Baño
- Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario Virgen Macarena
- Delia Herghea
- Oncology Institute Prof. Dr. I Chiricuta
- Oliver A. Cornely
- Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne
- Lena M. Biehl
- Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne
- Louis Bernard
- Centre hospitalo-universitaire de Tours
- M. Angeles Dominguez-Luzon
- Hospital Universitari de Bellvitge, Universitat de Barcelona
- Sofia Maraki
- University Hospital of Heraklion
- Olivier Barraud
- Université Limoges, INSERM U1092, Centre Hospitalier Universitaire de Limoges
- Maria Nica
- Infectious and Tropical Diseases Hospital “Dr. Victor Babes”
- Nathalie Jazmati
- Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne
- Frederique Sablier-Gallis
- Da Volterra
- Jean de Gunzburg
- Da Volterra
- France Mentré
- Université de Paris, INSERM, IAME
- Surbhi Malhotra-Kumar
- Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, University of Antwerp
- Marc J. M. Bonten
- Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University
- Maria J. G. T. Vehreschild
- Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne
- the ANTICIPATE Study Group
- DOI
- https://doi.org/10.1038/s41467-021-22269-y
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 10
Abstract
Here, the authors report the incidence of Clostridioides difficile infection (CDI) and assess potential clinical characteristics and biomarkers to predict CDI in 1,007 patients of 50 years and above receiving newly initiated antibiotic treatment.
