Advances in management of systemic lupus erythematosus

Abstract

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting multiple organ systems. In the past 40 years, prognosis for patients with SLE has improved significantly because of advances in the understanding of molecular mechanisms involved in the pathogenesis of disease, which has translated into early diagnosis and novel therapeutic strategies. This article will focus on three aspects that have shaped this transformation, namely; a revisit to diagnostic criteria, development of newer biomarkers, and incorporation of newer targeted therapies.

Keywords

• Advances
• connective tissue disorder
• systemic lupus erythromatosus