The Pan African Medical Journal (Apr 2021)
Laboratory capacity assessments in 25 African countries at high risk of yellow fever, August-December 2018
- Barbara Wilmot Johnson,
- Maurice Demanou,
- Gamou Fall,
- Jean-Luc Betoulle,
- Celestina Obiekea,
- Alison Jane Basile,
- Cristina Domingo,
- Christin Goodman,
- Eric Mossel,
- Chantal Reusken,
- Erin Staples,
- Joana Filipa Machado de Morais,
- Zoraima Neto,
- Paula Paixão,
- Yves Eric Denon,
- Mariette Glitho,
- José Mahinou,
- Therese Kagone,
- Emmanuel Nakoune,
- Kadidja Gamougam,
- Elisabeth Pukuta Simbu,
- Steve Ahuka,
- Jean-Vivien Mombouli,
- Cynthia Goma-Nkoua,
- Edgard Valery Adjogoua,
- Adamu Tayachew,
- Berhane Beyene,
- Bakary Sanneh,
- Modou Lamin Jarju,
- Alphonse Mendy,
- Dodzi Kofi Amelor,
- Lawrence Ofosu-Appiah,
- David Opare,
- Lorreta Antwi,
- Rexford Adade,
- N'Faly Magassouba,
- Sabado Fernandes Gomes,
- Samson Limbaso,
- Joel Lutomiah,
- Burgess Gbelee Jr,
- John Dogba,
- Issa Cisse,
- Zakou Idde,
- Chikwe Ihekweazu,
- Nwando Mba,
- Ousmane Faye,
- Oumar Faye,
- Amadou Alpha Sall,
- Zikan Koroma,
- Manuela Alphonse Juma,
- James Ayei Maror,
- Mawahib Eldigail,
- Adel Hussein Elduma,
- Rehab Elageb,
- Kossi Badziklou,
- Koba Adjaho Komla,
- John Kayiwa,
- Julius Julian Lutwama,
- Lee Hampton,
- Mick Norman Mulders
Affiliations
- Barbara Wilmot Johnson
- Scientific Laboratory Consulting, Laporte, Colorado, United States of America
- Maurice Demanou
- World Health Organization African Region Yellow Fever Laboratory, Ouagadougou, Burkina Faso
- Gamou Fall
- Institut Pasteur Dakar, Dakar, Senegal
- Jean-Luc Betoulle
- Scientific Laboratory, Atlanta, Georgia, United States of America
- Celestina Obiekea
- National Reference Laboratory, Nigeria Centre for Disease Control, Abuja, Nigeria
- Alison Jane Basile
- Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Fort Collins, Colorado, United States of America
- Cristina Domingo
- Robert Koch Institute, Berlin, Germany
- Christin Goodman
- Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Fort Collins, Colorado, United States of America
- Eric Mossel
- Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Fort Collins, Colorado, United States of America
- Chantal Reusken
- Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
- Erin Staples
- Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Fort Collins, Colorado, United States of America
- Joana Filipa Machado de Morais
- Instituto Nacional de Investigacao em Saude, Luanda, Angola
- Zoraima Neto
- Instituto Nacional de Investigacao em Saude, Luanda, Angola
- Paula Paixão
- Instituto Nacional de Investigacao em Saude, Luanda, Angola
- Yves Eric Denon
- National Public Health Laboratory, Cotonou, Benin
- Mariette Glitho
- National Public Health Laboratory, Cotonou, Benin
- José Mahinou
- National Public Health Laboratory, Cotonou, Benin
- Therese Kagone
- Centre Muraz, Bobo Dioulasso, Burkina Faso
- Emmanuel Nakoune
- Institute Pasteur, Bangui, Central African Republic
- Kadidja Gamougam
- Hôpital General De Reference Nationale, N'Djamena, Chad
- Elisabeth Pukuta Simbu
- National Institute for Biomedical Research, Kinshasha, Democratic Republic of Congo
- Steve Ahuka
- National Institute for Biomedical Research, Kinshasha, Democratic Republic of Congo
- Jean-Vivien Mombouli
- Institut National de Santé Publique, Brazzaville, Republic of Congo
- Cynthia Goma-Nkoua
- Institut National de Santé Publique, Brazzaville, Republic of Congo
- Edgard Valery Adjogoua
- Institut Pasteur de Côte d'Ivoire, Abidjan, Côte d'Ivoire
- Adamu Tayachew
- Ethiopian Public Health Institute, Virology and Rickettsiology Unit, Addis Ababa, Ethiopia
- Berhane Beyene
- World Health Organization Laboratory, Ethiopia
- Bakary Sanneh
- National Health Laboratory Services, Royal Victoria Teaching Hospital, Banjul, The Gambia
- Modou Lamin Jarju
- National Health Laboratory Services, Royal Victoria Teaching Hospital, Banjul, The Gambia
- Alphonse Mendy
- National Health Laboratory Services, Royal Victoria Teaching Hospital, Banjul, The Gambia
- Dodzi Kofi Amelor
- National Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana
- Lawrence Ofosu-Appiah
- National Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana
- David Opare
- National Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana
- Lorreta Antwi
- National Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana
- Rexford Adade
- National Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana
- N'Faly Magassouba
- Laboratoire de Reference des Fièvres Hémorragiques, Conakry, Guinée
- Sabado Fernandes Gomes
- Laboratoire National de Sante Publique, Bissau, Guinea-Bissau
- Samson Limbaso
- Center for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya
- Joel Lutomiah
- Center for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya
- Burgess Gbelee Jr
- National Public Health Reference Laboratory, National Public Health Institute of Liberia, Charlesville, Liberia
- John Dogba
- National Public Health Reference Laboratory, National Public Health Institute of Liberia, Charlesville, Liberia
- Issa Cisse
- Institut National de Santé Publique Laboratoire de Fièvre Jaune, Bamako, Mali
- Zakou Idde
- Niamey National Hospital, Niamey, Niger
- Chikwe Ihekweazu
- National Reference Laboratory, Nigeria Centre for Disease Control, Abuja, Nigeria
- Nwando Mba
- National Reference Laboratory, Nigeria Centre for Disease Control, Abuja, Nigeria
- Ousmane Faye
- Institut Pasteur Dakar, Dakar, Senegal
- Oumar Faye
- Institut Pasteur Dakar, Dakar, Senegal
- Amadou Alpha Sall
- Institut Pasteur Dakar, Dakar, Senegal
- Zikan Koroma
- National Public Health Laboratory, Lakka, Sierra Leone
- Manuela Alphonse Juma
- National Public Health Laboratory, Juba, South Sudan
- James Ayei Maror
- National Public Health Laboratory, Juba, South Sudan
- Mawahib Eldigail
- Public Health Laboratory, Khartoum, Sudan
- Adel Hussein Elduma
- Public Health Laboratory, Khartoum, Sudan
- Rehab Elageb
- Public Health Laboratory, Khartoum, Sudan
- Kossi Badziklou
- Laboratoire de Sérologie, Institut National d'Hygiène, Lomé, Togo
- Koba Adjaho Komla
- Laboratoire de Sérologie, Institut National d'Hygiène, Lomé, Togo
- John Kayiwa
- Uganda Virus Research Institute, Entebbe, Uganda
- Julius Julian Lutwama
- Uganda Virus Research Institute, Entebbe, Uganda
- Lee Hampton
- Gavi Secretariat, Geneva, Switzerland
- Mick Norman Mulders
- Department of Immunizations, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland
- DOI
- https://doi.org/10.11604/pamj.2021.38.402.28886
- Journal volume & issue
-
Vol. 38,
no. 402
Abstract
INTRODUCTION: accurate and timely laboratory diagnosis of yellow fever (YF) is critical to the Eliminate Yellow Fever Epidemics (EYE) strategy. Gavi, the Vaccine Alliance recognized the need to support and build capacity in the national and regional laboratories in the Global YF Laboratory Network (GYFLN) as part of this strategy. METHODS: to better understand current capacity, gaps and needs of the GYFLN laboratories in Africa, assessments were carried out in national and regional reference laboratories in the 25 African countries at high risk for YF outbreaks that were eligible for new financial support from Gavi. RESULTS: the assessments found that the GYFLN in Africa has high capacity but 21% of specimens were not tested due to lack of testing kits or reagents and approximately 50% of presumptive YF cases were not confirmed at the regional reference laboratory due to problems with shipping. CONCLUSION: the laboratory assessments helped to document the baseline capacities of these laboratories prior to Gavi funding to support strengthening YF laboratories.
Keywords
